Serum Survivin Increases in Prolactinoma

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Serum Survivin Increases in Prolactinoma

BACKGROUND Prolactinoma is the most common adult pituitary adenoma. Survivin is a member of the family of inhibitors of apoptosis proteins. Its expression is observed in many tumors. Survivin expression has shown in prolactinoma tissue before but no study exists showing serum survivin level. The aim of the present study was to investigate serum survivin levels in patients with prolactinoma and ...

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Serum Survivin in Patients with Rheumatoid Arthritis

Survivin is a member of the apoptosis inhibiting proteins. Suppression of apoptosis has been suggested as a key mechanism supporting selection and accumulation of distinct lymphocytes subsets in chronically inflamed joint tissues. The study was based on measuring the level of survivin in the sera of 35 RA and 15 matched control subjects. Results: Serum survivin is statistically higher in patien...

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[Prolactinoma].

Prolactin-secreting tumours (prolactinomas) are benign neoplasms constituting about 40 percent of all pituitary tumours. The incidence of these tumours varies with age and sex, occurring most frequently in females between 20 and 40-years-old. The clinical symptoms of prolactinomas are menstrual dysfunction and galactorrhea in women and loss of libido and potency in men. Differential diagnosis o...

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Survivin expression and serum levels in pancreatic cancer

BACKGROUND Survivin, an inhibitor of apoptosis, is overexpressed in pancreatic ductal adenocarcinoma (PDAC). Its expression is known to be associated with poor clinical outcome. However, to our knowledge, there has been no study to characterize its usefulness as a serum marker for human pancreatic cancer. Furthermore, the relation between survivin expression and the serum level of survivin has ...

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Prolactinoma in children and adolescents.

The evolution of prolactinomas in children and adolescents continues to be controversial. Girls have more prevalence of microprolactinomas and their signs and symptoms are related to hyperprolactinemia and the resulting hypogonadotrophic hypogonadism. In males, the greater incidence of macroadenomas results in the presence of neuro-ophthalmologic signs. The larger prevalence of macroadenomas in...

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ژورنال

عنوان ژورنال: Journal of Clinical Medicine Research

سال: 2015

ISSN: 1918-3003,1918-3011

DOI: 10.14740/jocmr2098w